UKMi Pandemic Flu |

Information

Introduction

This section of the UKMi website provides access to material produced by UKMi and other bodies relating to seasonal and H1N1  influenza, with a focus on the current outbreak. These resources will be updated as the outbreak, and information related to it, develops. This section of the website will be suspended once the outbreak is no longer an active issue.

• Breastfeeding - oseltamivir and zanamivir  (updated December 2011)   UKMi Medicines Q&A
• Drug interactions
  • Methotrexate - concomitant use with oseltamivir  (September 2011)  UKMi Medicines Q&A
  • Warfarin - interaction with oseltamivir and zanamivir  (July 2011)  UKMi Medicines Q&A
• PGDs - Local examples of PGDs for Pandemrix®, Celvepan® and trivalent seasonal flu vaccine  NeLM PGD portal
• Pregnancy  (UK Teratology Information Service - UKTIS) requires UKTIS registration
  • Seasonal flu vaccine (20/10/10) access to full guideline requires UKTIS registration
  • AH1N1v influenza vaccines (20/10/10) access to full guideline requires UKTIS registration
  • Management of pregnant women during an influenza A (H1N1) (Swine flu) pandemic  (16/12/10) access to full guideline requires UKTIS registration 
  • Oseltamivir (16/12/10) access to full guideline requires UKTIS registration 
  • Zanamivir (16/12/10)   access to full guideline requires UKTIS registration
• Renal dysfunction
  • Oseltamivir in renal impairment (November 2012)  UKMi Medicines Q&A
  • Oseltamivir with renal replacement therapies (November 2012  UKMi Medicines Q&A
  • Zanamivir in renal impairment or with renal replacement therapies (October 2011) Medicines Q&A

• Fact sheet on Tamiflu (oseltamivir)  (updated 24/11/2010)  NHS Direct Medicines Fact Sheet 

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Other sources

• Health Protection Agency
  • HPA guidance on use of antivirals for the treatment and prophylaxis of influenza V3 (Dec 2011, reviewed Oct 1012)
  • Managing outbreaks of acute respirtatory illness in care homes (October 2012) 
  • HPA pandemic influenza strategic framework (October 2012)
    
    
• Department of Health - 2012/13

  • Influenza Season 2012/13 - Use of antiviral medicines (December 2012)

  • Flu vaccination programme extended to all children (July 2012) 
  • Seasonal flu plan: Winter 2012/13 (May 2012)

 

• Department of Health - 2010/11
  • Influenza season 2010/11 - use of antivirals in primary care (10 December 2010)
  • Treatment guidelines for patients with influenza 2010/2011 in secondary care (14 December 2010)
  • Flu vaccination for pregnant women (16 December 2010)
  • Seasonal flu vaccination for pregnant women clarification of advice in the Green Book (23 December 2010)
  • 2010/11 Seasonal influenza: prescription of antivirals - CMO letter (21 December 2010)
  • Vaccine Update Special news alert edition: seasonal flu vaccination (December 2010)
  • Supply and availability of antivirals for children under 1 year of age - CPhO letter (January 2011)
    
  • Seasonal flu vaccine uptake and vaccine supply - CMO letter (6 January 2011)
    
• Department of Health - 2009 archive
  • Pandemic H1N1 2009 influenza: Clinical management guidelines for pregnancy (Oct 2009)

  • Pandemic H1N1 2009 influenza: Clinical management guidelines for adults and children (Oct 2009)

  • Clinical professionals brief on swine flu vaccination (28/10/2009)

  • Pregnancy, Breastfeeding and Swine Flu A/H1N1

  • Dosage of oseltamivir in children under one year of age with swine flu (24/09/2009
    
    

• MHRA

  • UK ADR analysis. Influenza antivirals - oseltamivir (Tamiflu) and zanamivir (Relenza) (4 February 2010)

  • Safety review of pandemic vaccines and antivirals (Drug Safety Update October 2010)

  • Seasonal flu vaccines and risk of febrile convulsions in children (December 2010)
    
    

NHS Choices

Royal Pharmaceutical Society

• Seasonal influenza web resource for pharmacists

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Medicines information provision in the event of a critical influenza outbreak

These two guidelines support UKMi local and regional services plan to deliver service continuity in the event of a critical influenza outbreak.  They are intended as a guide only as circumstances will vary according to local conditions and service priorities.

• Advice for provider Chief Pharmacists and their teams
• Availability of regional services
• Guidance on prioritising work for regional services